Welcome to MISCore

The MISCAN Core, or MISCore, is a Python modelling platform for discrete-event microsimulation. It enables researchers to rapidly develop models for various applications. MISCore is developed by the department of Public Health of Erasmus MC, University Medical Center Rotterdam and is written in Python, a high-level programming language known for its readability. It was initially designed to implement the MISCAN family of models to simulate non-communicable diseases in a population and evaluate screening strategies for those diseases. Active implementations include cancers of the colon, lung, breast, prostate, pancreas, bladder, cervix, oesophagus and stomach, as well as dementia and visual acuity. It has been used to estimate benefits and harms of screening and treatments, as well as for methodological issues surrounding screening trials and cost-effectiveness. The framework has been released under a public license for users to implement their own models.

Although specifically designed for modelling diseases and effects of screening in population, the generic set up of the framework allows for other applications as well. Tools are included for model calibration, risk-stratification, Quality-of-Life adjustment, and cost-effectiveness analysis. An extensive documentation is maintained to educate new users.

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